For myself, I collect Stan Lee SS comics for the sheer joy that they bring me. It's never about the money as I don't plan to sell any of them anytime soon. I also have a couple Stan Lee and Humberto Ramos signatures on one comic because I like both and respect both artists very much. I've loved Spider-Man for pretty much all my life and collect only him. I also have a Stan Lee autograph that is just a picture of him and that's it. Not a comic. That's my most prized possession.
I collect comics because of the artwork and because of the storytelling. Lee was a great person who made a lot of people happy, including myself. That's what it's all about for me. If my collection is worth $20,000 or $0.20, it makes it worth it knowing I have a piece of history.