"Best" is very subjective, it probably depends on your uncertainty and acceptable margin of error tolerances. And possibly how good your financial projection analysis skills and software are, and how deep you care to dig for direct or assumed comparable information. If you have a phd in financial engineering you'll probably have a better guess than most of us, but how much better? I don't think it'd be that much. Just too many unknowns.
I don't think you'll get too far other than vague generalities over time that are still occasionally untrue (statistically relevant). "ASM ratio variants on average has higher print run than She Hulk ratio variants, except when there's a special reason it doesn't. " but how much higher? and what are the special exceptions? and does it even matter since we can't calculate either number?
So for easy math, lets say it's a given there were 85,000 copies printed.
Could there ever be a case there were over 850 copies of a 1:100?