I doubt it, Bedlam was hyped for a long time before, and then the NYCC variants being over paid for prior to the launch of the actual book, turned it into an out and out frenzy, plus it had like 7 or 8 covers.
EoW will be high because of the cover, and a popular writer, but I would wager it falls around the high teens, maybe low twenties.
All that being said, small print runs dont make a book, just like variants dont stop a book. Quality and desirability rule the day.
Nick Spencer said offical print run for regular Bedlam was ~24607, so I could see with everyone(boardies and retailers) not wanting to get caught off guard that this could reach 25K+