So whats more impressive, a high value first appearance or a strong run of hard to find issues. A similar point, if you had, say Superman 1-100 and wanted to raise some money (space wasn't an issue) would you sell the unrestored VG #1 or the VG to VF 2-100 with equivalent value for the same $$$$?
Seeing a strong collection has always struck me as much more impressive, but the flipe sid is that there's little WOW factor for tht uninitiated. Show your uncle, the baseball card collector, a Superman 1 and he probably congratulates you, show him 2-100 and he might shrug.
In the end what do we individually appreciate more. I would prefer the single key to the larger run. It was one of the reasons I sold off 90% of my Spidermans, I got sick of owning issues from the lat 60's to 70's which had god-awful art and stories. That it got better in the 80's was great but all those books are so easy to find I could never get excited about collecting them.