I totally love the character of Gwenpool! The books so far are a great read as it is fun and light. It's a great break from other books that take themselves too seriously.
I pick up this book every week and try and collect those insane Gwenpool appearances (Holiday Specials, Rocket & Groot, and Champions to name a few). She adds a levity to books that she appears in.
Do I believe she will catch on? I seriously hope so. Marvel is trying to get her involved in some other titles other than her own. I think she'd make a great team up with Squirrel Girl. Currently, I think her pairing with Kate Bishop aka Hawkeye works well (from a limited sample... 1 issue so far).