Feels good to complete a run, doesn't it? I'm not sure if I have a complete run of anything...except maybe Eagle Comics from 1945...it was two issues...
It does, but I found that for myself I had to keep it selective or my head would explode. I started working on every damn mid-size bronze run out there and damn near went insane from SVTU, Freedom Fighters, Prez, Champions, Stalker, Secret Society of Super Villains, etc.
Remaining sets now are just Avengers (mind you, I mean only 1-402), Iron Man (same thing, original run, 1-332), Defenders (1-152) and the entire Marvel Godzilla run from childhood, mostly because Herb Trimpe and Dan Green autographed the whole thing for me when I was a teenager.
Everything else got read once more and dealt off in trade. But I'm off-topic, sorry!