Usually not. I am guilty of piecing together a complete ASM run, but that is the only title of its kind for me. Instead, I try to focus on cool covers, rare books, good deals, favorites from my youth, high grades, and/or diversity. There are many titles that I have no general interest in, but truely enjoy owning a select issue or two. I recently bought a "Don Wilson of the Navy" comic with a silly ghost cover. It is a great book, but hunting down the rest of that series is the last thing I want to do.