Well, Motion Picture Funnies Weekly no. 1 comes to mind - once a top five book tied with Superman 1 in value (at a time when Whiz 2(1) and Detective 27 were about the same!). The elephant in the room must be the Donald Duck books like Donald Tells About Kites and the March of Comics issues (4, 20, etc.), all top twenty books that have fallen out of favor.
The rarer Boy Explorers 2 made the cut-off for part of the 70's on the top 50 lists, which if I recall correctly, started in Overstreet number 7. Before that, the books were broken out only by title, and that was a few preceding editions only, not the first few editions.
One interesting note about the old-school valuation of books was the lack of cover-centric mania: no Detective 31, no Fantastic 3, and certainly no Suspense 3. Action 2 was in the top ten, Action 3 maybe the top twenty, and 4 and 5 were still worth more than issue 7 with its great cover!!