I read my way and completed 1-126. Seemed like a good issue to stop at with a cover recreation of issue one. That was a few years ago. Recently, a buddy of mine had some duplicates from his collection and gave me about 70 issues, including most of the Byrne run. I think sometime in the next year, I'll pick it up again and continue reading through until issue 300. Then I'll see what happens.
I'm doing the same thing with ASM.
The only series I've read from the beginning and still read the new issues as they are released today in the modern age is Daredevil.