Animated, but in Brad Bird-like hands. There have been a few animated TV shows with the Fantastic Four, and you can see how in the wrong hands it doesn't go over so well.For film I think they need to go photorealistic, cutting edge groundbreaking. A techno excellence wonder-to-behold jawdropper. Something that makes headlines technologically and gets butts in seats.
Make it epic, galactic, pack it with that Jack Kirby cosmic chariots-of-the-gods stuff. Use the core material and blow people's minds with the grand-fantasy of it all. What it's meant to be. Surfer, Galactus, Skrulls, Doom, worlds, dimensions, POWER, spectacle. All of it.
Put the "Fantastic" back in FF. Where anyone with a single geek-cell in their body has to go see for themselves.