Ok, best is a subjective term, she is probably the most popular/largest fanbase? The highest number of comic book appearances for any Marvel character created since 2000? Best overall strong female lead? For all the characters listed, I would say Spider Gwen has the best shot at competing, but she is too new IMO. Winter Soldier is a great example, maybe a better overall character, phenomenal storyline, but he is another male character in a sea of them.
I will just change it to "one of the best" to make it easy. She is a female derivative of Marvels second most popular hero behind Spiderman. It creates a huge fanbase, just like DC creating a female derivative of their #1 villain.