If I had 10,000 bb cards, would I be encouraged to ditch them? Or if I had 10,00 stamps? Or coins? I think people are focusing too much on the size of the collection...or the space it takes up...or possibly the work involved in maintaining the collection. I have to say, none of that is a problem for me.(as long as I use short boxes and not the long ones) And I'm going to go ahead and assume that I'm not the only comic collector who doesn't consider his collection to be a burden. I know there are collectors out there, probably many many, who do. I wholeheartedly agree with you that "there comes a point at which our treasure can frankly become a burden", but I'll never reach that point, even if I live to be 100...for me, there's no such thing as "ones you don't care about". So for some, pruning is advisable and acceptable, for others (including me), not so much. It's all fun for me. I enjoy collecting comics. I wouldn't enjoy pruning.